Characteristic

 

Sodium orthovanadate is the inorganic compound with the chemical formula Na₃VO₄·2H₂O (sodium orthovanadate dihydrate). It is a colorless, water-soluble solid.

Chemical formula:Na₃VO₄

Molar mass:183.908 g/mol

Appearance:white solid

Density:2.16 g/cm³, solid

Melting point:858 °C (1,576 °F; 1,131 K)

Solubility in water:22.17 g/100 mL

Solubility:insoluble in ethanol

Crystal structure:cubic

 

Application

 

Inhibitor of protein tyrosine phosphatase and alkaline phosphate Sodium orthovanadate is used in protein analysis in molecular biology and acts as an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and kinases. It is also used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It serves as a reagent in the development of matrix Chip that utilizes surface-immobilized antibodies. Further, it is utilized for the preservation of protein tyrosyl phosphorylation state in cells and cell lysates.